Perinatal mortality is affected by many things but ventilation plays a major factor in the hospital treatment. HFO (high frequency ventilation) is a gentle ventilation method that is especially effective for neonates and premature babies.

Compared with continuous mandatory ventilation (CMV), HFO ventilation has much less pressure swing at any MAP and this greatly reduces physical injury to the pulmonary alveoli.

Japan has one of the world's lowest perinatal mortality rates. One reason is adoption of the latest technology. Metran HFO ventilators are used in nearly 90% of NICUs in Japan and we are glad to be able to contribute to the high level of neonatal care in Japan.

Humming Vue is a high value, full-featured, flexible neonatal HFO ventilator. It is a volume generator ventilator using piston technology to guarantee the volume delivered in every stroke is exactly according to the setting in any respiratory conditions.

It produces the precise stroke volume (SV) to obtain a specified amplitude pressure (ΔP). SV is similar to tidal volume in conventional ventilation. A fixed SV is guaranteed no matter how the lung compliance changes.

Our technology allows us to precisely control piston movement to within 13 microns. Humming Vue allows fine setting of stroke volume with resolution as fine as 0.2 mL. This is critical when treating very small babies.

Due to constant feedback, our system can maintain the same HFO Vte even after changing the MAP setting.